The Postgraduate Institute of Medicine is managed by the Board of Management which is the principal administrative and academic authority of the Institute. Present Board of Management members are as follows.
WEF 01/07/2023
| Professor SD Jayaratne (Chairperson) | UGC Appointed Member |
| Professor Senaka Rajapakse | Director/PGIM |
| Professor Chandanie Wanigatunge | Deputy Director/PGIM |
| Mr K R Uduwawala | Nominee of the Secretary/Ministry of Education |
| Mr S Janaka Sri Chandraguptha | Secretary/Ministry of Health |
| Ms Visakha Amarasekere | Nominee of the Secretary/Ministry of Finance |
| Dr Asela Gunawardena | Director General of Health Services |
| Dr P W C Panapitiya | Deputy Director General of Medical Service |
| Professor Vajira H W Dissanayake | Nominee/Faculty of Medicine, University of Colombo |
| Professor Vasanthi Pinto | Nominee/Faculty of Medicine, University of Peradeniya |
| Professor T P Weerarathna | Nominee/Faculty of Medicine, University of Ruhuna |
| Professor MG Sathiadas | Nominee/Faculty of Medicine, University of Jaffna |
| Professor RC Fernandopulle | Nominee/Faculty of Medical Sciences, University of Sri J’pura |
| Professor SJ De S Hewavisenthi | Nominee/Faculty of Medicine, University of Kelaniya |
| Professor M Umakanth | Nominee/Faculty of Health Care Sciences, Eastern University |
| Professor Sisira Siribaddana | Nominee/Faculty of Medical & Allied Sciences, Rajarata University |
| Professor FR Fernando | Nominee/Faculty of Medicine, University of Moratuwa |
| Professor AM Attygalla | Nominee/Faculty of Dental Sciences, University of Peradeniya |
| Professor S G Yasawardene | Nominee/Faculty of Dental Sciences, University of Sri J’pura |
| Professor H Janaka de Silva | UGC Appinted Member |
| Professor Jayantha Jayawardena | UGC Appinted Member |
| Professor Nandadeva Samarasekera | UGC Appinted Member |
| Professor Arjuna de Silva | UGC Appinted Member |
| Dr Harsha Cabral | UGC Appinted Member |
| Dr(Mrs) Malkanthi Galhena | UGC Appinted Member |
| Professor S Karunaratne | Council Nominee |
| Ms Padmini Ranaweera | Council Nominee |
| Co-opted Members | |
| Dr Ranjan Dias | Chairperson/AAAEC |